Tobramycin

Product Description

Classification Type Tobramycin
CAS NO. 32986-56-4 Other names
MF C18H37N5O9 EINECS NO. 251-322-5
Place of origin China Grade standard   USP grade
Purity 99% Appearance White  powder
HS CODE 2941909099 packing 1kg/Tin
Shelf life 2 MOQ
Application RAw  Material

描述

Specification

Tobramycin is also known as tobramycin or nepaxin. One of the aminoglycoside antibiotics. Usually sulfate. The antibacterial spectrum is similar to that of gentamicin, but the antibacterial activity against Pseudomonas aeruginosa (PseudChemicalbookomonasaeruginosa) is 2 to 4 times stronger, and it is also effective against gentamicin-resistant strains; it is also effective against other G-bacteria. The antibacterial activity is slightly inferior to that of gentamicin. Can be used to treat a variety of serious infections caused by Pseudomonas aeruginosa and other G-bacteria.

Items Specification
Appearance White to off-white powder
Assay (on the anhydrous basis) ≥900μg/m
 Residue on ignition ≤0.3%
Chromatographic purity(TLC Any individual spot≤1.0%
PH 9.0 ~ 11.0
Water ≤7.5%
Specific optical rotation +138°~ +148°
Clarity of solution Clear, if the solution is turbid, it shall not exceed the turbidity of 0.5# turbidity standard solution
Colour If colour develops, the colour of test solution should not be more intense than yellow or yellow-green 2# standard colour solution
Bacterial endotoxins <2.0EU/mg
Residual solvents Ethanol                     ≤2000ppm

Acetaldehyde                ≤450ppm

Microbial limit TAMC                      ≤1000cfu/g

TYMC                      ≤100cfu/g

E.Coli               Should be absent/g

 Conclusion The product complies with USP and In-house Specifications

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