Pharmaceuticals API Bacteriostatic Antibiotic Chloramphenicol

What is Chloramphenicol?

Chloramphenicol is an antibiotic useful for the treatment of a number of bacterial infections. This includes use as an eye ointment to treat conjunctivitis. By mouth or by injection into a vein, it is used to treat meningitis, plague, cholera, and typhoid fever. Chloramphenicol topical formulations were used in the past to treat superficial eye and ear infections.

Product Description

Classification Type Chloramphenicol
CAS NO. 56-75-7 Other names
MF C6H7N3O2 EINECS NO. 200-287-4
Place of origin China Grade standard   USP grade
Purity 99% Appearance White  powder
HS CODE 2941400000 packing 25kg/drum
Shelf life 3 MOQ
Application RAw  Material

描述

Specification

Chloramphenicol is a broad-spectrum bacteriostatic ANTIBIOTIC, which is the first choice for the treatment of typhoid fever and paratyphoid fever, one of the special drugs for the treatment of anaerobic bacteria infection, and then for the treatment of various infectious diseases caused by sensitive microorganisms. Due to the serious adverse reactions are used less and less. It is used to treat infections caused by Bacilli typhi, bacilli dysenteriae, Escherichia coli, Bacilli influenzae, Brucella, pneumococcus, etc.

Items Specification
Appearance A white, greyish-white or yellowish-white, fine, crystalline powder or fine crystals
Solubility Slightly soluble in water, freely soluble in alcohol and in propylene glycol
Melting point 149℃ – 153℃
IR The sample spectrum complies with the reference standard spectrum
Acidity or alkalinity Positive
Specific optical rotation +18.5 °to +20.5°
Related substances(TLC) Not more than 0.5%
Chlorides Not more than 100 ppm
Loss on drying Not more than 0.5%
Sulfated ash Not more than 0.1%
Assay (on dried basis) 98.0% to 102.0%
 Conclusion The product complies with the standard EP9.0

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